12
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13
Nov
2024
类器官与器官芯片技术网络研讨会-仪器信息网
China
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Webinar
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![[Translate to chinese:] Multicolor fixed STED image. Inner ear section, mouse, TauSTED Xtend 589 on AF488 and TauSTED Xtend 775 on AF633-Phalloidin. Sample courtesy of Dennis Derstrof, Klinik für Hals-, Nasen und Ohrenheilkunde, Universität Marburg & Prof. Dr. Dominik Oliver aus dem Institut für Physiologie und Pathophysiologie, Abteilung für Neurophysiologie, Universität Marburg.](/fileadmin/_processed_/c/a/csm_Inner_ear_section_mouse_multicolor_fixed_TauSTED_Xtend_1a1a0b424b.jpg "[Translate to chinese:] Multicolor fixed STED image. Inner ear section, mouse, TauSTED Xtend 589 on AF488 and TauSTED Xtend 775 on AF633-Phalloidin.")
细胞活成像的纳米级扩展
新的STED显微技术方法——TauSTED Xtend，使得在纳米级别下对活体完整样本进行扩展多色成像成为可能。通过结合空间和寿命信息，TauSTED Xtend提供了额外一层信息，允许在极低的光剂量下分辨小细节并在整体结构中解析它们。
![[Translate to chinese:] Five-color FLIM-STED](/fileadmin/_processed_/a/3/csm_5-color_FLIM-STED_9d88340e60.jpg "[Translate to chinese:] Five-color FLIM-STED")
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Super-resolved STED spectroscopy
Molecular interactions are key in cellular signalling. They are often ruled or rendered by the mobility of the involved molecules.