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人工智能显微成像能够高效检测稀有事件
对稀有事件进行定位和选择性成像是许多生物样本研究过程的关键。然而，由于时间限制和高度的复杂性，有些实验无法做到，从而限制了获得新发现的前景。通过基于人工智能的显微成像检测稀有事件，这种工作流程将智能样本导航、图像采集工具和人工智能驱动的图像分析等不同功能融合起来共同协作，能够克服上述局限性。
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荧光入门介绍
荧光是George Gabriel Stokes于1852年首次报道的一种现象。他观察到萤石在紫外线照射后开始发光。荧光是光致发光的一种形式，是指一种材料被光照射后会发射出光子。发射光的波长比激发光更长。这种效应又称为斯托克斯位移。
![[Translate to chinese:] The intraoperative OCT showed the ellipsoid had separated from the inner retina with focal attachment to the retinal pigment epithelium (RPE). Images provided by Mr. Robert Henderson](/fileadmin/_processed_/d/b/csm_Ellipsoid_separated_from_the_inner_retina_with_focal_attachment_to_the_retinal_pigment_epithelium_5c9220260c.jpg "[Translate to chinese:] The intraoperative OCT showed the ellipsoid had separated from the inner retina with focal attachment to the retinal pigment epithelium (RPE). Images provided by Mr. Robert Henderson")
![[Translate to chinese:] Cancer cells](/fileadmin/_processed_/6/b/csm_Cancer_cells_f5e991d1c9.jpg "[Translate to chinese:] Cancer cells")
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![[Translate to chinese:] Pancreatic Ductal Adenocarcinoma with 5 biomarkers shown – SMA, PanCK PCK26, PanCK AE1, Vimentin, and Glut1.](/fileadmin/_processed_/3/a/csm_Pancreatic_Ductal_Adenocarcinoma_with_5_biomarkers_412898c37f.jpg "[Translate to chinese:] Pancreatic Ductal Adenocarcinoma with 5 biomarkers shown – SMA, PanCK PCK26, PanCK AE1, Vimentin, and Glut1.")
借助多重成像深入了解胰腺癌的复杂性
胰腺癌是一种很难治疗的肿瘤疾病。Cell DIVE多重成像可以视觉呈现30种生物标志物以探测胰管癌的微环境。此面板可以检查肿瘤组织多个层级的问题，包括淋巴细胞、血管新生、转移、侵袭、炎症、缺氧、代谢和免疫。多重成像和分析可以对肿瘤组织中的许多生物活动提供更为深入的洞察信息，从而可以深入研究这些信息。
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![[Translate to chinese:] Raw widefield and THUNDER image of calcium transients in Drosophila embryos. Courtesy A. Carreira-Rosario, Clandinin laboratory, California, USA.](/fileadmin/_processed_/7/6/csm_Calcium_transients_in_Drosophila_embryos_teaser_34991ebcaa.jpg "[Translate to chinese:] Raw widefield and THUNDER image of calcium transients in Drosophila embryos. Courtesy A. Carreira-Rosario, Clandinin laboratory, California, USA.")
Central Nervous System (CNS) Development and Activity in Organisms
This article shows how studying central nervous system (CNS) development in Drosophila-melanogaster embryos expressing a GCaMP calcium indicator in the neurons can be improved with a THUNDER Imager.
![[Translate to chinese:] Cell DIVE Multiplex Imaging Solution](/fileadmin/_processed_/0/6/csm_Cell_DIVE_dad174e320.jpg "[Translate to chinese:] Cell DIVE Multiplex Imaging Solution")
