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09 Apr 2025

CYTO U Live Web Event

United States Webinar
10 Apr 2025
Developing embryos of different species at different stages during the elongation of their posterior body axis, from left to right in developmental time. The labelled regions in red depict a region of undifferentiated cells called the tailbud, with the corresponding region generated from that tissue shaded in grey. Upper row: lamprey; middle row: catshark; bottom row, zebrafish. This figure has been adapted from the following publication: Steventon, B., Duarte, F., Lagadec, R., Mazan, S., Nicolas, J.-F., & Hirsinger, E. (2016). Species tailoured contribution of volumetric growth and tissue convergence to posterior body elongation in vertebrates. Development, 2016. 143(10):1732-41

How to Study Gene Regulatory Networks in Embryonic Development

Join Dr. Andrea Boni by attending this on-demand webinar to explore how light-sheet microscopy revolutionizes developmental biology. This advanced imaging technique allows for high-speed, volumetric…
[Translate to chinese:] The role of extracellular signalling mechanisms in the correct development of the human brain

在神经发育过程中,细胞是如何相互交流的?

细胞间通信是大脑发育过程中一个必不可少的过程,它受到多种因素的影响,包括细胞的形态、粘附分子、局部细胞外基质和分泌囊泡。在本次网络研讨会上,您将了解到对这些机制更深入的理解是如何推动对神经发育障碍的理解的。
[Translate to chinese:] In vivo imaging of a mouse pial and cortical vasculature through a glass window (ROSAmT/mG::Pdgfb-CreERT2 mouse meningeal and cortical visualization following tamoxifen induction and craniotomy). Courtesy: Thomas Mathivet, PhD

神经血管病理学之窗

探索先天性免疫如何在神经血管病变后持续产生有害影响,以及能够对这些事件进行纵向研究的技术发展。
[Translate to chinese:] THY1-EGFP labeled neurons in mouse brain processed using the PEGASOS 2 tissue clearing method, imaged on a Leica confocal microscope. Neurons were traced using Aivia’s 3D Neuron Analysis – FL recipe. Image credit: Hu Zhao, Chinese Institute for Brain Research.

借助人工智能,揭示复杂而密集的神经元图像中的洞察

神经元的3D形态学分析通常需要使用不同的成像模式,捕捉多种类型的神经元,并在各种密度下相连的传统Leica SP8显微镜采集多达解神经元的形态,这对许多研究人员来说仍然是一个耗时的挑战。

如何从根本上简化成像设备的工作流程

本集MicaCam中,来自伦敦大学学院(UCL)的特邀嘉宾Christopher Thrasivoulou博士将从成像设备的角度讨论使用Mica的优势。他将讨论如何简化复杂生物系统的成像工作流程并实现自动化。这有助于科学家节省为获取有意义的量化分析结果而投入的时间和精力。为了举例说明此类工作流程,他还会展示如何对荧光标记的固定斑马鱼胚胎进行多色成像。
[Translate to chinese:] Zebrafish heart showing the ventricle with an injury in the lower area

斑马鱼心脏损伤后心肌细胞增殖现象

本期MicaCam聚焦于斑马鱼相关研究(斑马鱼)。不同于其他哺乳动物的心脏细胞,斑马鱼的心脏细胞能够在受损之后完全再生。
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