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See More Than Just Your Image
Despite the emergence of new imaging methods in recent years, true 3D resolution is still achieved by Confocal Laser Scanning Microscopy (CLSM). Through a combination of novel, extremely fast scanning…
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Super-resolved STED spectroscopy
Molecular interactions are key in cellular signalling. They are often ruled or rendered by the mobility of the involved molecules.
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通用 PAINT – 动态超分辨率显微镜
超分辨率显微技术在过去十年中彻底革新了生物学研究。这些技术让我们能够以接近蛋白质大小的分辨率观察细胞内的各个组成部分。然而,对活细胞进行成像仍然是大多数超分辨率技术面临的挑战。在这种背景下,uPAINT(纳米尺度拓扑成像通用点积累)技术受到了广泛关注。这种单分子方法通过动态成像活细胞中持续标记的任意膜生物分子,实现了超高分辨率成像,并能追踪单个分子的运动轨迹。
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Sample Preparation for GSDIM Localization Microscopy – Protocols and Tips
The widefield super-resolution technique GSDIM (Ground State Depletion followed by individual molecule return) is a localization microscopy technique that is capable of resolving details as small as…
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超分辨率 GSDIM 显微镜
纳米级技术GSDIM(基态耗尽显微镜后单分子返回)提供了细胞内蛋白质和其他生物分子空间排列的详细图像。目前市场上已有首个商业系统(Leica SR GSD),它正在帮助将GSDIM技术推广给更多研究实验室和成像中心的用户。