Leica Microsystems: 显微镜科学与教学知识中心

显微镜科学与教学知识中心

徕卡显微系统的知识库提供有关显微镜学科的科学研究和教学材料。内容旨在对显微镜初学者、有经验的显微镜操作实践者和使用显微镜的科学家在他们的日常工作和实验有所帮助。这里有探索交互式教程和应用笔记，你可以找到你需要的显微镜的基础知识以及前沿技术——快来加入徕卡显微知识社区，分享您的专业知识！

模式生物研究

模式生物是研究人员用来研究特定生物学过程的物种。它们具有与人类相似的遗传特征，通常用于遗传学、发育生物学和神经科学等研究领域。选择模式生物的原因通常是它们在实验室环境中易于保持和繁殖、生成周期短，或能够产生突变体来研究某些性状或疾病。

Developing embryos of different species at different stages during the elongation of their posterior body axis, from left to right in developmental time. The labelled regions in red depict a region of undifferentiated cells called the tailbud, with the corresponding region generated from that tissue shaded in grey. Upper row: lamprey; middle row: catshark; bottom row, zebrafish. This figure has been adapted from the following publication: Steventon, B., Duarte, F., Lagadec, R., Mazan, S., Nicolas, J.-F., & Hirsinger, E. (2016). Species tailoured contribution of volumetric growth and tissue convergence to posterior body elongation in vertebrates. Development, 2016. 143(10):1732-41

How to Study Gene Regulatory Networks in Embryonic Development

Join Dr. Andrea Boni by attending this on-demand webinar to explore how light-sheet microscopy revolutionizes developmental biology. This advanced imaging technique allows for high-speed, volumetric…

[Translate to chinese:] Intestinal organoids label with FUCCI reporter to follow cell cycle dynamics. Courtesy of Franziska Moos. Liberali lab. FMI Basel (Switzerland).

双视野光片显微镜，适用于大型多细胞系统

展示复杂多细胞系统的动态是生物学中的一个基本目标。为了应对在大型时空尺度上进行活体成像的挑战，作者在《自然·方法》杂志上发表的一篇论文中介绍了一种开放式多样本双视野光片显微镜。研究发现，Viventis LS2 Live显微镜在以单细胞分辨率成像大型样本方面取得了显著进展。