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High-pressure freezing: Revealing functional mechanisms of synaptic transmission
Learn more about applying optogenetic stimulation in the EM ICE and how this technology has the potential to reveal structural and functional mechanisms of synaptic transmission. Get a detailed…
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从器官到组织再到细胞:使用宽场显微镜分析 3D 标本
在传统的宽场显微镜下从厚的三维样本中获取高质量的数据和图像是具有挑战性的,因为存在失焦光的干扰。在本次网络研讨会中,Falco Krüger 展示了THUNDER成像仪如何通过Computational Clearing技术使这一切成为可能。
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Workflows and Instrumentation for Cryo-electron Microscopy
Cryo-electron microscopy is an increasingly popular modality to study the structures of macromolecular complexes and has enabled numerous new insights in cell biology. In recent years, cryo-electron…
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Computational Clearing - 增强3D标本成像
本次网络研讨会旨在阐明有助于THUNDER显微成像仪实现三维样品可视化的关键规格,并改进研究人员的成像相关工作流程。
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THUNDER成像:高效、灵活、易操作,让您的日常成像工作流更轻松
本次网络研讨会将展示 THUNDER 在许多不同生命科学应用中的多功能性和性能:从计数视网膜切片中的细胞核和癌组织切片中的 RNA 分子,到监测阿拉伯芥幼苗中的钙波等等。
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Expanding the Limits of Electron Microscopy Sample Preparation
Capturing the intricate changes in fine structure or in cell dynamics with conventional cryo solutions can be challenging sometimes. Leica Microsystems has developed a new cryo platform, the Leica EM…
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Live Cell Isolation by Laser Microdissection
Laser microdissection is a tool for the isolation of homogenous cell populations from their native niches in tissues to downstream molecular assays. Beside its routine use for fixed tissue sections,…
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非聚焦离子束研磨的实践应用
机械抛光不仅费时费力,而且还会产生伪影,干扰扫描电子显微镜(SEM)的电子背散射衍射(EBSD)结果或光学显微镜研究。相比之下,离子束研磨可以消除干扰数据分析和图像解读的伪影。