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将动态活细胞数据融入超微结构
采用徕卡Nano的工作流程，可以避免过去如海底捞针似的寻找。利用光电关联显微技术，在适当的时间直接鉴别出正确的细胞，并将动态的活细胞数据融入其超微结构中。
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Exploring the Structure and Life Cycle of Viruses
The SARS-CoV-2 outbreak started in late December 2019 and has since reached a global pandemic, leading to a worldwide battle against COVID-19. The ever-evolving electron microscopy methods offer a…
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Fast, High-quality Vitrification with the EM ICE High Pressure Freezer
The EM ICE High Pressure Freezer was developed with a unique freezing principle and uses only a single pressurization and cooling liquid: liquified nitrogen (LN2). This design enables three major…
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使用增强功能电子显微镜研究大脑切片中的突触
神经科学的一个基本问题就是突触的结构与其功能特性之间有何关系？过去几十年，电生理学揭示了突触传递机制，而电子显微镜（EM）深入探索了突触形态。用于关联突触生理学和超微结构的方法可以追溯到20世纪中叶。目标是获得突触传递的快照，即捕获电子显微照片中的动态过程。
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Advancing Cell Biology with Cryo-Correlative Microscopy
Correlative light and electron microscopy (CLEM) advances biological discoveries by merging different microscopes and imaging modalities to study systems in 4D. Combining fluorescence microscopy with…
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High-pressure freezing: Revealing functional mechanisms of synaptic transmission
Learn more about applying optogenetic stimulation in the EM ICE and how this technology has the potential to reveal structural and functional mechanisms of synaptic transmission. Get a detailed…
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Workflows and Instrumentation for Cryo-electron Microscopy
Cryo-electron microscopy is an increasingly popular modality to study the structures of macromolecular complexes and has enabled numerous new insights in cell biology. In recent years, cryo-electron…
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EM TIC 3X进行离子束刻蚀简介
在这篇文章中，您可以了解到如何通过使用EM TIC 3X离子束研磨仪的离子束蚀刻工艺来优化样品的制备质量。文中简介了EM TIC 3X仪器特性，以此解释如何灵活地将该设备应用于各类研究领域的样本制备工作中。本文将帮助读者了解离子束刻蚀工艺的基本原理，及其如何在各种应用中获得高分辨率的SEM图像。本文也将介绍EM TIC…
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研究天然聚合物精细细节的微观结构
本报告评估了结合使用冷冻宽幅离子束铣削和扫描电子显微镜（cryo-BIB-SEM）对低温稳定柔性聚合物的微观结构进行成像和分析的潜能。报告介绍了使用cryo-BIB-SEM对易损天然聚合物进行检查的结果，例如番茄果皮和木材，还分析了聚合物表面形态和多种微观结构特性。
