AI meets Deep Visual Proteomics (DVP) to Advance Disease Research
In this webinar, Dr. Andreas Mund introduces Deep Visual Proteomics (DVP) – a cutting-edge platform that integrates AI-powered tissue modeling with spatially resolved, untargeted proteomics. He…
Microscopy and AI Solutions for 2D Cell Culture
This eBook explores the integration of microscopy and AI technologies in 2D cell culture workflows. It highlights how traditional imaging methods—such as brightfield, phase contrast, and…
人工智能驱动的乳腺癌研究多重染色成像空间分析工具
乳腺癌(BC)是女性因癌症死亡的主要原因,研究查肿瘤微环境(TME)对于阐明肿瘤进展机制至关重要。利用超多标染色空间蛋白质组学技术系统地绘制肿瘤微环境图谱可以提高精准免疫肿瘤学的能力。在这里,我们将基于人工智能的高倍空间分析应用于BC组织,研究免疫细胞类型和生物标记物,从而深入了解受免疫疗法反应的TME分子机制。
Focus on Long-Term Imaging in 3D with Light Sheet Microscopy
Long-term 3D imaging reveals how complex multicellular systems grow and develop and how cells move and interact over time, unlocking critical insights into development, disease, and regeneration.…
Ultramicrotome Sectioning of Polymers for TEM Analysis
We demonstrate the capabilities of the UC Enuity ultramicrotome from Leica Microsystems for preparing ultrathin sections of polymer samples under both ambient and cryogenic conditions. By presenting…
Biomarker Discovery with Laser Microdissection
Explore the potential of spatial proteomics workflows, such as Deep Visual Proteomics (DVP), to decipher pathology mechanisms and uncover druggable targets.
Altered protein expression, abundance, or…
Volume EM and AI Image Analysis
The article outlines a detailed workflow for studying biological tissues in three dimensions using volume-scanning electron microscopy (volume-SEM) combined with AI-assisted image analysis. The focus…
A Guide to C. elegans Research – Working with Nematodes
Efficient microscopy techniques for C. elegans research are outlined in this guide. As a widely used model organism with about 70% gene homology to humans, the nematode Caenorhabditis elegans (also…
How a Breakthrough in Spatial Proteomics Saved Lives
Toxic epidermal necrolysis (TEN) is a rare but devastating reaction to common medications like antibiotics or gout treatments. It begins innocuously, often as a rash, but can escalate rapidly into…