Long-term 3D imaging reveals how complex multicellular systems grow and develop and how cells move and interact over time, unlocking critical insights into development, disease, and regeneration.…
We demonstrate the capabilities of the UC Enuity ultramicrotome from Leica Microsystems for preparing ultrathin sections of polymer samples under both ambient and cryogenic conditions. By presenting…
Explore the potential of spatial proteomics workflows, such as Deep Visual Proteomics (DVP), to decipher pathology mechanisms and uncover druggable targets.
Altered protein expression, abundance, or…
The article outlines a detailed workflow for studying biological tissues in three dimensions using volume-scanning electron microscopy (volume-SEM) combined with AI-assisted image analysis. The focus…
Efficient microscopy techniques for C. elegans research are outlined in this guide. As a widely used model organism with about 70% gene homology to humans, the nematode Caenorhabditis elegans (also…
Toxic epidermal necrolysis (TEN) is a rare but devastating reaction to common medications like antibiotics or gout treatments. It begins innocuously, often as a rash, but can escalate rapidly into…
In this article, Dr. Andrew T. Huang, MD, FACS, otolaryngologist and a head and neck reconstructive surgeon, shares how digital 3D surgical visualization with the MyVeo headset from Leica Microsystems…